The Department of Surgery

The University of Chicago

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Mitchell C. Posner, MD

Physician Profile

Printable Version
General Surgery
Professor of Surgery
Chief of General Surgery, Director of Surgical Oncology Fellowship Program, and Director for the Center of GI Oncology
5841 S. Maryland, MC 5094, Chicago, IL 60637
Phone: 773-834-0156

Clinical Interests:
Dr. Posner joined the faculty at the University of Chicago in 1995. Since that time the University of Chicago Hospitals' international reputation for excellence in surgical oncology, and particularly GI Oncology, has been greatly enhanced by his presence and leadership. Well-versed in all facets of cancer surgery, Dr. Posner specializes in cancers of the esophagus, stomach, liver, pancreas, colon, and rectum, as well as malignant melanoma and soft tissue sarcoma. Dr. Posner is highly regarded and known for his experience in handling the most difficult and complex cases.

Clinical specialties:

General surgery
Surgical oncology
Pancreatic cancer
Liver cancer
Esophageal cancer
Melanoma
Sarcomas

Academic Interests:

Dr. Posner is equally accomplished in oncology research, as displayed by his heavy involvement in designing and guiding significant clinical trials in gastrointestinal cancers. In the laboratory, Dr. Posner is investigating molecular genetic events associated with gene therapy of pancreatic, esophageal, and liver tumors and translating new findings for innovative treatment approaches to these cancers. He is an award-winning teacher, as well as a popular figure among residents at the University of Chicago Cancer Research Center and throughout the University of Chicago Hospitals.

Education:
Board Certification: General Surgery
Board Certification: Surgical Oncology
M.D.: State University of New York, Buffalo, NY
Internship: University of Colorado, Denver, CO
Residency: University of Colorado, Denver, CO
Fellowship: Memorial Sloan-Kettering Cancer Center, New York, NY

Representative Publications:
Kimchi ET, Posner MC, Park JO, Darga TE, Kocherginsky M, Karrison T, Hart J, Smith KD, Mezhir JJ, Weichselbaum RR, Khodarev NN. Progression of Barrett's metaplasia to adenocarcinoma is associated with the suppression of the transcriptional programs of epidermal differentiation. Cancer Res 2005; 65(8):3146-54

Wu PC, Langerman A, Ryan CW, Hart J, Swiger S, Posner MC. Surgical treatment of gastrointestinal stromal tumors in the imatinib (STI-571) era. Surgery 2003; 134(4):656-65; discussion 665-6

Gupta VK, Park JO, Jaskowiak NT, Mauceri HJ, Seetharam S, Weichselbaum RR, Posner MC. Combined gene therapy and ionizing radiation is a novel approach to treat human esophageal adenocarcinoma. Ann Surg Oncol 2002; 9(5):500-4

Posner MC, Alverdy J. Hand-assisted laparoscopic surgery for cancer. Cancer J 2002; 8(2):144-53

Lew JI, Gooding WE, Ribeiro U, Jr., Safatle-Ribeiro AV, Posner MC. Long-term survival following induction chemoradiotherapy and esophagectomy for esophageal carcinoma. Arch Surg 2001; 136(7):737-42; discussion 743

Buell JF, Rosen S, Yoshida A, Labow D, Limsrichamrern S, Cronin DC, Bruce DS, Wen M, Michelassi F, Millis JM, Posner MC. Hepatic resection: effective treatment for primary and secondary tumors. Surgery 2000; 128(4):686-93

Year Started in Practice:1988 

Practice Location(s):Center for Advanced Medicine
5758 S. Maryland Avenue
Chicago, IL 60637 
Memberships:American Society of Clinical Oncology
Society for Surgery of Alimentary Tract
Society of Surgical Oncology
Society of University Surgeons 
Languages Spoken:English 


Published Works