The Department of Surgery

The University of Chicago

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Mitchell C. Posner, MD

Faculty Profile

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General Surgery
Professor
Chief of General Surgery, Director of Surgical Oncology Fellowship Program, and Director for the Center of GI Oncology
5841 S. Maryland, MC 5094, Chicago, IL 60637
Phone: 773-702-6120

Clinical Interests:
Internationally recognized as an expert in the management of upper gastrointestinal cancers, Mitchell Posner, MD, ranks among the country's best doctors, according to Chicago magazine and the physician rating service Castle Connolly Medical Ltd. Dr. Posner couples his skill as a cancer surgeon with an intense commitment to multidisciplinary care, providing his patients with optimal outcomes. His peers regard him as an authority on all GI cancers, especially cancers of the esophagus and pancreas.

Clinical specialties:

General surgery
Surgical oncology
Pancreatic cancer
Whipple procedure for pancreatic cancer
Liver cancer
Esophageal cancer
Esophageal diseases
Melanoma
Sarcomas

Academic Interests:

Dr. Posner's work goes beyond the operating room. In the lab, he focuses on the molecular basis of malignancies, which has enabled him to design and guide groundbreaking clinical trials for cancers of the pancreas, esophagus, colon, stomach, rectum, and liver. With more than 30 years of experience, he has won dozens of awards and published 200 articles, abstracts, and book chapters.

In 1995, after serving as director of the Colorectal and Gastrointestinal Cancer Center at the Pittsburgh Cancer Institute, Dr. Posner came to the University of Chicago Medical Center as chief of surgical oncology and director of the Surgical Oncology Fellowship Program. In 2005, he was appointed Chief of the Section of General Surgery. In 2006, he became vice-chairman of the Department of Surgery, and a year later was named vice-chairman of clinical affairs. Dr. Posner has won the University's Robert J. Baker Award for Excellence in Teaching, as well as the Basic Science and Clinical Research Award from the Society of Surgical Oncology.

Currently, Dr. Posner serves as chairman of the Gastrointestinal Committee of the American College of Surgeons Oncology Group (ACOSOG), the only national, surgically-focused cooperative group dedicated to clinical trials research. He is also president of the Society for Surgical Oncology, the largest professional organization of cancer surgeons in the world, and is on the editorial board for esteemed industry journals, including Annals of Surgery, Annals of Surgical Oncology and Journal of the American College of Surgeons.

Education:
Board Certification: General Surgery
Board Certification: Surgical Oncology
M.D.: State University of New York, Buffalo, NY
Internship: University of Colorado, Denver, CO
Residency: University of Colorado, Denver, CO
Fellowship: Memorial Sloan-Kettering Cancer Center, New York, NY

Representative Publications:
Kimchi ET, Posner MC, Park JO, Darga TE, Kocherginsky M, Karrison T, Hart J, Smith KD, Mezhir JJ, Weichselbaum RR, Khodarev NN . Progression of Barrett's metaplasia to adenocarcinoma is associated with the suppression of the transcriptional programs of epidermal differentiation. Cancer Res 2005; 65 (8) : 3146-54

Wu PC, Langerman A, Ryan CW, Hart J, Swiger S, Posner MC . Surgical treatment of gastrointestinal stromal tumors in the imatinib (STI-571) era. Surgery 2003; 134 (4) : 656-65; discussion 665-6

Gupta VK, Park JO, Jaskowiak NT, Mauceri HJ, Seetharam S, Weichselbaum RR, Posner MC . Combined gene therapy and ionizing radiation is a novel approach to treat human esophageal adenocarcinoma. Ann Surg Oncol 2002; 9 (5) : 500-4

Posner MC, Alverdy J . Hand-assisted laparoscopic surgery for cancer. Cancer J 2002; 8 (2) : 144-53

Lew JI, Gooding WE, Ribeiro U, Jr., Safatle-Ribeiro AV, Posner MC . Long-term survival following induction chemoradiotherapy and esophagectomy for esophageal carcinoma. Arch Surg 2001; 136 (7) : 737-42; discussion 743

Buell JF, Rosen S, Yoshida A, Labow D, Limsrichamrern S, Cronin DC, Bruce DS, Wen M, Michelassi F, Millis JM, Posner MC . Hepatic resection: effective treatment for primary and secondary tumors. Surgery 2000; 128 (4) : 686-93

Year Started in Practice:1988 

Practice Location(s):Center for Advanced Medicine
5758 S. Maryland Avenue
Chicago, IL 60637 
Memberships:American Hepato-Pancreato-Biliary Association
American Society of Clinical Oncology
American Surgical Association
Society for Surgery of Alimentary Tract
Society of Surgical Oncology
Society of University Surgeons 
Languages Spoken:English 


Published Works